Welcome to
the CRP Clinic
Renewing Hope, Fulfilling Dreams, Embracing New Life.
We specialise in advanced treatments to address pregnancy loss and fertility challenges.
I'm looking
for help with miscarriages
I need
help to get pregnant
I want to
check on my baby's health
The CRP Clinic was founded by Professor Hassan Shehata, a renowned Consultant Obstetrician and Gynaecologist, specialised in Maternal Medicine.
With extensive training and expertise, focusing on recurrent miscarriages and pregnancy complications, Professor Shehata is dedicated to delivering the highest standard of care to our patients. His passion for improving reproductive health and his commitment to excellence have shaped the values and principles that define CRP Clinic.
Miscarriages
Miscarriages can occur at any stage of pregnancy and leave couples feeling overwhelmed and heartbroken. If you have experienced two or more consecutive pregnancy losses, known as recurrent miscarriages, we recognise the unique challenges you face.
Our team offers comprehensive testing and personalised treatment plans tailored to your specific needs. Our goal is to identify the root causes behind recurrent miscarriages and develop a customised approach to optimise your chances of a successful pregnancy.
Causes
Immune System Issues
Overactive immune factors like antinuclear antibodies (ANA) and thyroid antibodies, such as thyroid peroxidase (TPO) thyroid thyroglobulin antibodies (TTG) and thyroid stimulating hormone receptor antibodies (TSH-RAB), have also been associated with an increased risk of miscarriage, indicating a potential role of an overactive immune system in pregnancy loss.
Hormonal Imbalances
Polycystic Ovary Syndrome (PCOS) is a condition that can hinder successful pregnancies. Studies have revealed a link between PCOS and recurrent miscarriages, potentially attributed to factors like insulin resistance, elevated insulin levels, and heightened androgen levels often observed in PCOS.
Thyroid problems can also elevate the risk of miscarriage. Although the precise mechanisms are not fully understood, thyroid hormones are crucial for the development of various bodily tissues. Abnormal thyroid hormone levels can negatively impact fertility and pregnancy outcomes.
Abnormalities in the Womb
Issues related to the neck or structure of the uterus can contribute to pregnancy loss mainly in the second trimester after 14 weeks gestation.
Cervical incompetence refers to a weakened cervix that may struggle to support the growing fetus as the pregnancy progresses. This condition can affect women who have experienced late miscarriages or premature deliveries. Additionally, invasive treatments of the cervix for abnormal smear tests can increase the risk.
Womb malformations are another potential cause of miscarriage. These congenital conditions can vary in type and severity, including uterus didelphys, unicornuate uterus, bicornuate uterus (heart-shaped), and septate uterus. It remains unclear whether these malformations directly cause recurrent miscarriages and surgical interventions to correct them must be carefully considered.
Polyps and fibroids, non-cancerous growths in the womb could lead to failed implantation and, rarely, miscarriages. In some cases, surgical removal of fibroids may be necessary.
Infections
Bacterial Vaginosis (BV) has been associated with late miscarriages, premature deliveries, and post-delivery womb infections. BV occurs due to a disruption in the normal vaginal bacteria balance and is the most common cause of vaginal discharge among women of childbearing age.
Symptoms of BV may include thin white or grey discharge, a distinct fishy odour that intensifies after intercourse, genital area itching or irritation, and a burning sensation during urination. Diagnosis confirmation typically involves a vaginal swab and antibiotics are prescribed to treat BV once it is confirmed.
Group-B Streptococcus (GBS) is one of the many bacteria that normally live in our bodies and which usually cause no harm. GBS may be passed from person to person through direct physical contact. It is not a sexually transmitted disease. Testing for GBS is not routinely offered to all pregnant women in the UK. There is evidence that group B Strep can cause late miscarriage (death of the baby between 14 and 24 weeks of pregnancy) and stillbirth (death of the baby after 24 weeks of pregnancy up until the baby is born). We don’t understand why group B Strep causes stillbirths or late miscarriages in some babies but not others. However, thankfully stillbirths are relatively uncommon in the UK, and group B Strep is not a common cause of them, accounting for around 1% of all stillbirths before labour in high-income countries. So, it is rare that someone carrying GBS will have a stillbirth or late miscarriage caused by GBS. We’re not aware of any evidence that group B Strep causes earlier miscarriages (before 14 weeks of pregnancy).
High Sperm DNA Fragmentation
High levels of sperm DNA damage have been linked to an increased risk of miscarriage and poorer pregnancy outcomes, whether conception occurs naturally or through assisted reproductive techniques.
At our clinic, we offer a test to assess DNA damage in sperms. Men are advised to ejaculate 2-3 times within the week leading up to the test but abstain from sexual activity for 48 hours before the test. The sperm sample is sent to a laboratory in Copenhagen for analysis, preserved in liquid nitrogen.
Abnormal results from the test usually prompt a consultation with a urologist for further evaluation. Several factors can contribute to high DNA fragmentation, such as excess weight, smoking, infections, elevated temperatures, exposure to heavy metals, chemotherapy, certain medications, and varicocele (enlarged veins in the scrotum). It is crucial to investigate and address these factors to improve sperm health and reduce the risk of miscarriage.
If treatment is recommended, a complimentary repeat test is offered after 3 to 6 months to assess the impact of the intervention on sperm integrity. To ensure availability, we advise scheduling the appointment in advance.
Chronic Histiocytic Intervillositis (CHI)
Autoimmune or allergic phenomena were identified and treatment include immune therapy of different kinds and for different durations. The diagnosis is a histopathology one and include idiopathic inflammatory lesion, intervillous space location, extensive maternal infiltration of inflammatory mononuclear cells (monocytes, lymphocytes, histiocytes) in particular CD68, intervillous fibrinoid deposits and trophoblast erosions of varying degree, diffuse (massive) or multifocal infiltration.
We understand that experiencing a miscarriage can be a lonely and isolating journey, we want you to know that you are not alone. Our caring and supportive team is here to provide you with the empathy, understanding, and expertise you need to navigate through this challenging time.
If you or a loved one has experienced recurrent miscarriages and are seeking compassionate care and support, we encourage you to reach out to us. Our dedicated team of specialists is available at both locations to provide comprehensive care tailored to your needs.
Assisted Conception
We offer extensive investigations and treatments for subfertility, addressing both male and female factors. Our range of fertility treatments includes advanced techniques such as in vitro fertilisation (IVF) and intrauterine insemination (IUI) to increase your chances of achieving a successful pregnancy.
As a satellite clinic to Kings Fertility, we ensure that our patients receive the highest standard of care and access to cutting-edge fertility technologies.
Treatments We Offer
Superovulation
Superovulation is a fertility treatment option for women with ovulation disorders, irregular menstrual cycles, or infrequent release of eggs. This technique involves using medications, such as Letrozole, to stimulate the ovaries and promote the growth of follicles. Our clinic success rate average is 10% per cycle with best results in the first 4 cycles. The process includes:
- Follicle Stimulation: Medications are administered to stimulate the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which help the ovaries produce more follicles. This medication is typically taken for a few days during the menstrual cycle.
- Ultrasound Assessment: Regular ultrasound monitoring is conducted to assess the size and number of follicles and adjust the medication dosage accordingly. The ultrasound scans also help determine the timing of ovulation triggers.
- Ovulation Induction: An injection of human chorionic gonadotropin (HCG) is given to trigger ovulation and the release of mature eggs.
- Timed Intercourse: Based on the ovulation trigger injection, timed intercourse is planned to optimise the chances of conception.
Intrauterine Insemination (IUI)
- Sperm Preparation: The male partner provides a semen sample, which is processed to isolate the healthiest and most viable sperm.
- Insemination: Using a small catheter, the prepared sperm is gently inserted into the uterus, optimising the chances of fertilisation.
- Post-Procedure: After the IUI procedure, the woman can resume normal activities immediately.
- Sperm Preparation: The male partner provides a semen sample, which is processed to isolate the healthiest and most viable sperm.
For couples where the male partner has high sperm DNA fragmentation, we offer an advanced technique called microfluidic separation (Zymot). Zymot is a sperm selection device that isolates sperm with the least amount of DNA damage, potentially increasing the chances of successful pregnancy in eligible couples.
In Vitro Fertilisation (IVF)
The IVF procedure includes:
- Ovarian Stimulation: The woman receives hormone medications to stimulate the ovaries and produces multiple eggs. Blood tests and ultrasound scans are conducted to monitor follicle development and ensure the eggs are collected at the optimal time.
- Egg Retrieval: The eggs are collected using a guided needle aspiration procedure performed at our partner clinic, Kings Fertility.
- Fertilisation: The collected eggs are fertilised with prepared sperm in a laboratory dish. If fertilisation is successful, embryos start to develop and are monitored for two to five days. Embryos can also be cryopreserved (frozen) for future use.
- Embryo Transfer: A selected number of embryos are transferred to the uterus using a special catheter guided by ultrasound. This step is performed at our partner clinic, Kings Fertility.
- Pregnancy Test: Approximately two weeks after the embryo transfer, a pregnancy test is performed to confirm the success of the treatment.
Your fertility journey is not one you have to face alone. Our team is dedicated to providing ongoing support, guidance, and counselling throughout the entire process.
We are committed to being by your side, offering reassurance, answering your questions, and celebrating your milestones as you move closer to realising your dream of starting or growing your family.
Baby Scans
At CRP Clinic, we understand the importance of comprehensive care and support during pregnancy, especially when it comes to monitoring the health and development of your baby.
Our Fetal Medicine team utilises advanced ultrasound technology to provide a range of specialised scans and assessments to ensure the well-being of your baby. From early pregnancy to the third trimester, we offer a variety of fetal medicine services tailored to meet your specific needs.
| Feature | NHS | High-Street Scan Clinics |
CRP Clinic: Consultant-Led Fetal Medicine |
|---|---|---|---|
| Main Purpose | Routine screening offered to the general population | Reassurance scans and keepsake images | Comprehensive medical assessment of your baby |
| Who Performs the Scan | Sonographer | Sonographer | Consultant in Fetal Medicine |
| Appointment Length | Short and structured | Varies | Longer, unhurried consultation with time for discussion |
| Accurate Pregnancy Dating | ✅ Yes | ✅ Yes | ✅ Yes |
| Assessment of Baby’s Development | Basic checks | Very limited | Detailed and systematic anatomical assessment |
| Screening for Trisomy 21, 18 & 13 | ✅ Combined screening | ❌ Not offered | ✅ Combined screening ± NIPT available |
| Nuchal Translucency Measurement | ✅ Included | Variable | ✅ Specialist-level assessment |
| Early Detection of Major Structural Concerns | Limited by time and scope | ❌ Not designed for this | ✅ Advanced early anatomy review |
| Placental Assessment | Basic review | ❌ Not included | ✅ Detailed evaluation incl. Doppler studies |
| On-Site Blood Tests | ✅ Available | ❌ Not available | ✅ Available |
| Immediate Medical Interpretation | Limited | ❌ Not provided | ✅ Consultant-led explanation |
| Continuity of Care | Depends on local pathway | ❌ No medical follow-up | ✅ Ongoing consultant oversight |
| Follow-Up & Pregnancy Planning | According to NHS guidelines | ❌ Not provided | ✅ Individualised proactive planning |
Services We Offer
Nuchal Scans
Anomaly Scans
Also known as mid-pregnancy ultrasounds, anomaly scans are comprehensive and detailed examinations typically performed between 20 and 24 weeks of pregnancy. These scans play a vital role in detecting any structural abnormalities in the fetus, assessing the baby’s well-being, and evaluating the placenta and amniotic fluid.
Growth Scans
Cervical Scans
3D/4D Ultrasound
NIPT (or Non-Invasive Prenatal Diagnosis Testing)
NIPT analyses cell free DNA in maternal blood and gives a strong indication of whether the fetus is at high or low risk of having Trisomy 21 (Down’s Syndrome), Trisomy 18 (Edwards Syndrome) or Trisomy 13 (Patau Syndrome).
The test identifies 99%, but not all, of the fetuses with Trisomy 21, 97% of fetuses with Trisomy 18 and 92% of fetuses with Trisomy 13. The NIPT test can be performed in women carrying one or two alive fetuses at any stage in their pregnancy from 10 to 32 weeks.
The results from the test will generally be available within one weeks and we will notify you as soon as we receive them by phone and email/letter.
In about 5% of cases the test does not give a result. This is due to technical problems with the analysis of the sample and does not suggest that there is a problem with the baby. If you want you can have the test repeated (at no cost) and there is a 50% chance that the test will give a result.
If the NIPT test shows that there is a high risk that the fetus has Trisomy 21 or 18 or 13 it does not mean that the fetus definitely has one of these defects. If you want to be certain if the fetus has one of these defects you should have CVS or amniocentesis.
If the NIPT test shows that there is a low risk (less than 1 in 10,000) that the fetus has Trisomy 21 or 18 or 13 it is unlikely that the fetus has one of these defects.
The NIPT test does not provide information on physical defects, such as heart or brain abnormalities and spina bifida, or fetal growth. It is therefore advisable that you still have nuchal ultrasound scans at 11-13 weeks and at 20-22 weeks to examine the fetal anatomy and at 32-36 weeks to examine the fetal growth.
Contact us today to schedule an appointment and let us be a part of your prenatal care journey.
Women's Health
Whether you’re seeking a routine check-up, a fertility assessment, or a private menopause clinic, our experienced team is here to provide personalised and routine care tailored to your needs.
Check-Ups and Assessments
Wellwoman Check-up
During this annual visit, our skilled and friendly gynaecologists will review your medical history, perform a thorough physical examination, including a pelvic ultrasound, and conduct relevant tests such as blood work. This comprehensive assessment allows us to identify any risks or concerns and provide appropriate preventive or diagnostic measures.
Fertility Check-up and Assessment
Hormonal tests and screenings for sexually transmitted diseases may also be recommended to gather a comprehensive understanding of your fertility potential. With this information, we can offer guidance, discuss any concerns, and explore potential treatment options if necessary.
Specialised Menopause Support
We offer a variety of treatment options to alleviate menopausal symptoms, such as hot flushes, mood swings, and vaginal dryness. Hormonal replacement therapy (HRT) is one effective treatment that can help manage these symptoms and reduce the risk of associated conditions like osteoporosis and heart disease. Our expert gynaecologists will work closely with you to develop an individualised treatment plan that addresses your specific needs and concerns.
Endometriosis Clinic
Endometriosis occurs when tissue similar to the lining of the uterus grows outside the womb, leading to symptoms such as pelvic pain, heavy menstrual bleeding, and fertility issues.
At our clinic, we offer a range of services aimed at effectively managing endometriosis and improving your quality of life. Our team of gynaecologists conducts thorough assessments to diagnose your condition and develop a personalised treatment plan tailored to your unique needs.
Treatment options may include medication to improve symptoms, hormonal therapy to regulate hormone levels, minimally invasive surgery to remove endometrial tissue, and fertility preservation strategies for those planning to conceive.
Advanced Gynaecological Scans
3D Scans
Saline Scans
Saline scans are particularly useful for detecting conditions such as polyps, fibroids, and uterine adhesions, which may contribute to infertility or recurrent miscarriages. By identifying these issues, we can develop targeted treatment strategies to address your gynaecological concerns and optimize your reproductive health.
HyFosy (Tubal Patency Check)
HyFosy is an effective method for evaluating tubal health and identifying blockages or abnormalities that may affect fertility. By confirming tubal patency, we can help determine the most appropriate fertility treatment options for you, whether it be natural conception or assisted reproductive techniques.
Surgical Procedures
Hysteroscopy
Hysteroscopy is particularly valuable for diagnosing and managing conditions such as uterine polyps, fibroids, adhesions (Asherman’s syndrome), and abnormal uterine bleeding. During the procedure, therapeutic interventions can be performed as necessary, including the removal of polyps, excision of adhesions, or endometrial biopsies for further evaluation. The procedure can be done under local anaesthesia, although we typically recommend sedation to enhance patient comfort during the process.
Manual Vacuum Aspiration (MVA)
Men's Health
We provide high-quality specialised care and support to promote men’s health and well-being. Our urologist specialises in men’s health, focusing on male fertility and overall well-being. We offer comprehensive assessments and tailored treatment plans to address male infertility concerns. Similar to our approach to women’s health, we also provide annual Wellman checks to proactively monitor men’s health and detect any potential issues.
Check-Ups and Assessments
Male Fertility Evaluation
Through advanced diagnostic techniques, we can identify potential causes of fertility issues and offer personalised treatment options. Lifestyle modifications, targeted therapies, and assisted reproductive techniques like IUI or IVF may be recommended based on individual needs and circumstances.
Wellman Check-up
During the visit, our experienced urologists conduct a thorough medical assessment, including a comprehensive medical history review. Vital signs, such as blood pressure, height, and weight, are measured.
We also offer a detailed testicular examination and, if necessary, a testicular ultrasound to assess testicular health. Additional blood tests, including PSA (Prostate-Specific Antigen), liver and kidney function tests, male and thyroid hormonal tests, full blood count, and diabetes screening, may be recommended to provide a comprehensive health assessment. A urine analysis may also be included as part of the evaluation process.
Low Testosterone Or Libido
Testosterone replacement is not recommended when a couple are planning to have children due to the negative impact on sperm production but alternative medication may be available that boosts the body’s own testosterone levels and the quality of sperm.
Erection Problems
Ejaculation Problems
Testicular Swellings
Men may experience testicular swellings that can be linked to fertility concerns, sometimes arising from conditions such as varicoceles or infections, which may impact sperm production and quality. While most cases are benign, persistent or painful swellings should be evaluated to rule out underlying issues such as hydroceles or, rarely, testicular cancer. Depending on the cause, treatments may include antibiotics, surgical intervention, or assisted reproductive techniques to improve fertility outcomes.
Urinary Symptoms and Prostate Health
Prostate cancer is very rare under the age of 50 but men with a strong family history or Afro-Caribbean origins may be more at risk. More commonly the prostate enlarges for benign reasons but the symptoms this cause can have a significant effect on quality of life. Infectious problems such as prostatitis can also give similar symptoms more commonly in younger men.
Appropriate and prolonged antibiotic treatment may be required but consideration of effects of infection and antibiotics on sperm production must also be considered.
At the Wellman Clinic, we are committed to providing high-quality care and support to promote men's health and well-being.
Our team of experts combines their skills and knowledge with a compassionate approach to ensure that each patient receives personalised attention and effective treatment options. By addressing male health concerns, including fertility issues and general well-being, we aim to empower men to take control of their health and lead fulfilling lives.
Pioneering approach
to fertility challenges
We promote cutting edge scientific medical approach to diagnose and treat miscarriages and failed IVF attempts.
High Success Rate
Our experienced team of specialists has achieved excellent success rates, with over 80% of our patients experiencing successful pregnancies following our tailored treatment plans.
Personalised care
Each patient we see is unique and we provide tailored strategies to address their specific circumstances and family planning goals.
Compassionate support
We understand that experiencing a miscarriage can be a lonely and isolating journey. We want you to know that you are not alone. Our caring and supportive team is here to provide you with the empathy, understanding, and expertise you need to navigate through this challenging time.
Holistic Care for Couples'
Health and Fertility
We understand the importance of addressing both men's and women's concerns when it comes to starting a family. We provide tailored Wellwoman & Wellman services along with thorough fertility screening and complementary therapies. Our aim is to support and improve overall health as couples embark on their journey to parenthood.
Key CRP Clinic Numbers
Recurrent Miscarriages
Live Birth Rate
IVF/ICSI
Clinical Pregnancy Rate
Live Birth Rate
Superovulation Program
Clinical Pregnancy Rate
Key Numbers
Latest CRP Clinic News
CRP Clinic Testimonials
We welcomed a healthy baby boy, Jack, on 23rd April 2024. Navigating a pregnancy after loss is an anxious time, but the staff at CRP are caring and offer advice and reassurance at every step. Dr Edge is simply amazing, and seeing our baby in 4D at our 10 week scan was a magical moment. We are so grateful to Professor Shehata, and your pioneering research and treatment into recurrent miscarriages. Without this, we would not have our son. We are forever grateful to you all.
Grace and Darren
Elaine and Ryan
Tess and Robin
From the moment we walked through their doors, CRP took charge of our journey with unwavering dedication and expertise. They not only provided medical care but also offered us emotional support every step of the way. Thanks to their guidance and skill, our dreams were realised, and we couldn’t be happier with the outcome. To anyone embarking on a similar journey, I wholeheartedly recommend CRP. Put your trust in them, and let them work their magic.
Kouroshi
I’m so thankful that we found the CRP Clinic: our initial appointment with Professor Shehata was the first time that we felt really listened to and detailed notes were taken about each pregnancy. Thorough testing uncovered three separate issues which were not picked up elsewhere. After starting treatment for high NK cells in January, I fell pregnant in April and gave birth to a beautiful baby girl in January. I have no doubt that her birth is a result of the testing, medication and advice that we received at the clinic.
L Wilson
We will be forever grateful to CRP Clinic for everything that they have done for us to get our baby here safely. After a missed miscarriage at 10 weeks and an ectopic pregnancy we didn’t have much hope that things would work out. We welcomed our beautiful baby boy in March and he wouldn’t be here without Professor Shehata’s work on reproductive immunology. The entire team at CRP went above and beyond for us. Dr Edge was amazing and a big support to us.
E Babmead
I have 2 beautiful babies from visiting Mr Shehata and his team on both separate occasions. We had 5 miscarriages when I did not have the treatment and can only deduct that the treatment was a huge success. I am very grateful for that. The journey is emotional and can be costly, my honest review is that you cannot expect to be counselled with part of your treatment and so you need to have any expectations of this aside.
Christine
The whole team at the CRP clinic have been incredible but we would like to take the opportunity to pay a particular thank you to Professor Shehata, Dr Edge, Professor Akolekar and all the midwife team who went above and beyond. We know that without their amazing help and kindness we would not be here today. We are also so grateful for Professor Shehata’s care during my wife’s ectopic pregnancy last year where he went above and beyond to ensure she was safe.
Chris
My husband and I have been patients with the CRP clinic since 2016 -2023. Professor Shehata and his team have gone above and beyond to help us achieve our dream of starting a family after so many medical problems and losses. We now have two beautiful children thanks to their tireless efforts to make this a success for us. They do everything to find the right medications and protocols to work with your medical issues, your body etc.
Lisa
We received excellent care throughout our IVF journey and cannot thank Mr Jan, Geri, Mr Shehata and the rest of the team for their care and attentiveness. I felt very safe and cared for, they took the time to offer me clear advice and I was offered a treatment plan based on the latest research and evidence based practice. We are so grateful for our healthy 4 month old son today, thanks to you.
Sarah and Bowie
I attended the CRP clinic after suffering from recurrent miscarriage at 8, 12 and 19 weeks. The pregnancy was successful and we had a healthy baby girl in October 2022. Dr Silva was my main doctor throughout the pregnancy and she was incredible at supporting parents who have been through loss. he midwives and nurses were extremely caring and the scans are all done very sensitively and in a style that is supportive for parents.
Julie
Mr Shehata is extremely knowledgeable and kind. He and his consultants, midwives and other staff are experts in dealing with anxious expectant mothers. The midwife line is a great service for questions outside regular appointments. I urge anyone suffering from unexplained pregnancy loss to book a consultation with Mr Shehata or to try to get an NHS referral. I’d say he’s a miracle worker and should be given a knighthood for services to women’s health.
Janie
After 5 losses I was starting to give up all hope of having a baby and being a mum. I wasn’t getting any answers as to why this kept happening. The clinic finally gave me the answers I needed and amazing support and I now have happy, healthy (and crazy) 2 and 4 year old boys. Forever grateful to the clinic and all the staff that made it possible.
Nicola
I’m a recurrent and late miscarriage sufferer. I was told these were “bad luck”. There was a reluctance to test and an even bigger reluctance to treat. I had to find my own way to your clinic. Thank goodness this clinic exists. I felt heard and I found hope. My littlest boy is here now because of this clinic and its willingness to treat! Thank you from the bottom of my heart. Finally there is some peace.
Kirsten
They gave me my little miracle. Within 4 weeks of being tested I was pregnant with my second daughter after having suffered 9 miscarriages. Dr Shehata is the most amazing person and the wider team couldn’t do enough to support me on my journey.
Victoria
The CRP Clinic
Meet The CRP Clinic Team
At CRP Clinic, we understand the emotional and physical challenges our patients face. That's why we have assembled a compassionate, empathetic, and responsive multidisciplinary team of specialists who collaborate to provide comprehensive care and support the moment you step into our clinic together with personalised attention and a warm, welcoming smile.
CRP Clinics Instagram
Start Your Journey Now: Take the Next Steps with the CRP Clinic
Contact us now to schedule a consultation and take the first step towards a fulfilling and joyful journey of parenthood.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
